--pain, loss of feeling, burning, "pins & needles", sleeping, phantom pains
in
hands/feet (forearms/lower legs)
--loss of hair around your ankles or wrists (because the nerves that support the skin are killed off at the extremities first, moving toward the trunk)
--reflux or stomach and intestinal conditions that can't be controlled by normal Rx (because they are based in nerve loss to these organs)
--inability to sweat on hands/feet, then lets/arms and later trunk - at that point you will BURN rather than sweat which is not a great way to wake up every morning