What are the best treatments for Alternating Hemiplegia Of Childhood?

Treatments for Alternating Hemiplegia of Childhood

Alternating Hemiplegia of Childhood (AHC) is a rare neurological disorder that typically begins in infancy or early childhood. It is characterized by recurrent episodes of paralysis that affect one side of the body or both sides alternately. The exact cause of AHC is still unknown, and there is currently no cure for the condition. However, there are several treatment options available to manage the symptoms and improve the quality of life for individuals with AHC.

1. Medications

Medications play a crucial role in managing the symptoms of AHC. The primary goal of medication is to control and prevent the episodes of paralysis. Different medications may be prescribed based on the specific symptoms and needs of each individual. Commonly used medications include:

• Flunarizine: This calcium channel blocker has shown some effectiveness in reducing the frequency and severity of paralysis episodes.


• Sodium channel blockers: Medications such as carbamazepine or lamotrigine may be prescribed to help prevent or shorten the duration of paralysis episodes.


• Benzodiazepines: These medications, such as clonazepam, can help manage dystonia and other associated movement disorders.

2. Physical and Occupational Therapy

Physical and occupational therapy can be highly beneficial for individuals with AHC. These therapies focus on improving motor skills, coordination, and overall physical function. Therapists may use various techniques, exercises, and assistive devices to help individuals with AHC gain better control over their movements and enhance their independence.

3. Assistive Devices

Assistive devices can greatly assist individuals with AHC in their daily activities. Devices such as braces, splints, or orthotics can provide support and stability to affected limbs. Wheelchairs or mobility aids may be necessary for those with severe mobility impairments. Communication devices, such as speech-generating devices or eye-tracking technology, can help individuals with speech difficulties to express themselves effectively.

4. Seizure Management

Seizures are common in individuals with AHC. Seizure management is an essential aspect of treatment. Antiepileptic medications may be prescribed to control and reduce the frequency of seizures. It is important for individuals with AHC to work closely with their healthcare team to find the most effective seizure management plan.

5. Supportive Care

Supportive care is crucial for individuals with AHC and their families. A multidisciplinary approach involving neurologists, physiotherapists, occupational therapists, speech therapists, and psychologists can provide comprehensive care and support. Regular follow-up visits, monitoring of symptoms, and adjustments to treatment plans are essential to ensure the best possible outcomes.

While there is no cure for Alternating Hemiplegia of Childhood, a combination of medications, therapies, assistive devices, seizure management, and supportive care can significantly improve the quality of life for individuals with AHC. It is important for individuals with AHC and their families to work closely with healthcare professionals to develop a personalized treatment plan that addresses their specific needs and symptoms.