. To what extent is HS caused by genetic factors?
There are two forms of HS, familial and sporadic. The HS family is one in which
the affected individual has blood relatives who are also affected, although the degree of
involvement can be very different. Assumes at least 40% of the cases, while our research
in the Spanish population indicate that we might get to correspond to 85% of the cases. The HS family is
a hereditary disease and is directly caused by genetic factors, i.e. mutations
specific genes in our genome, which can be identified through analysis genéticomoleculares.
For its part, the HS sporadic is one in which the affected individual do not have blood relatives with
HS. This can be explained both because his HS does not have genetic origins as by the fact that yes
the have and have not seen other family members affected - either because the mutation original founder of
the disease has occurred in that particular patient (who may have descendants affected), well
because the chance of the inheritance has done that you do not have affected relatives known.
In any case, it should be clear that as a general rule, not all the descendants of a patient
HS will inherit the disease.