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What is the prevalence of Inappropriate Sinus Tachycardia?

How many people does Inappropriate Sinus Tachycardia affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Inappropriate Sinus Tachycardia

Inappropriate Sinus Tachycardia (IST) is a condition characterized by an abnormally fast heart rate at rest, unrelated to any underlying medical condition or physical exertion. While the exact prevalence of IST is not well-established, it is considered a relatively rare condition. Studies suggest that IST affects approximately 1-3% of the general population, predominantly affecting young to middle-aged women. However, due to underdiagnosis and misdiagnosis, the true prevalence may be higher. IST can significantly impact an individual's quality of life, causing symptoms such as palpitations, fatigue, and exercise intolerance.



Inappropriate Sinus Tachycardia (IST) is a condition characterized by an abnormally fast heart rate at rest, unrelated to any physiological need or external factors. It is a relatively rare disorder, making it challenging to determine its exact prevalence. However, studies suggest that IST affects approximately 1-3% of the general population, with a higher prevalence among females.


IST is often diagnosed in individuals between the ages of 15 and 50, and its symptoms can significantly impact a person's quality of life. The condition is characterized by a resting heart rate exceeding 100 beats per minute, accompanied by symptoms such as palpitations, fatigue, shortness of breath, and exercise intolerance.


While the exact cause of IST remains unclear, it is believed to involve dysfunction in the sinus node, the heart's natural pacemaker. The condition can be challenging to diagnose, as other underlying medical conditions and medications can also cause tachycardia.


Treatment for IST typically involves a combination of lifestyle modifications and medication. Beta-blockers, calcium channel blockers, and ivabradine are commonly prescribed to help control heart rate. In severe cases, catheter ablation may be considered to target and disrupt the abnormal electrical pathways causing the rapid heart rate.


It is important for individuals experiencing symptoms of IST to consult with a healthcare professional for an accurate diagnosis and appropriate management.


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4 answers
To date (10-09-2017), the prevalence of Inappropriate Sinus Tachycardia is unknown.

Posted Sep 9, 2017 by Matthew_94 3340
Considered rare but I believe that will change.

Posted May 22, 2018 by Sara 2550
It is much more common in women,almost exclusively female about countries I do not know ..

Posted Feb 2, 2019 by npb 1400

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- Got diagnosed in 2013, after a year of having bad symptoms. Have been taking Metroprolol, Bisoprolol, Ivabradine, Verapamil and Tambocor. All of them didn't work and I got side-effects of them. - First ablation: October 2014. They ablated the sinu...
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One night I was sleeping and after two hours of sleeping I woke up with a very intense fatigue on the left side and I got up very desperately, then I started to have tachycardia that reached up to 124 beats per minute, and symptoms such as difficulty...
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On 1st November 2014, I was cycling to work in the evening. I reached a downhill stretch and naturally stopped pedaling and allowed the bicycle to do the work. The next thing I remember, is that I was waking up on the side of the road, my bicycle a b...

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