Panhypopituitarism is a potentially life-threatening endocrine disorder that is classified by a distinct absence of pituitary hormones, which, consequently, causes hormone insufficiencies in the other endocrine glands, most notably, the thyroid, adrenals, and ovaries/testes due to the pituitary being unable to release the hormones necessary to trigger the function of these target glands. This dangerous domino effect, then, is what leads to the rise of the symptoms we face every day and the reason why we take our medicine and need constant blood work and appointments etc.