In my experience, I believe people with Panhypopituitarism can work in many fields. But, if someone were to have SOD/ONH (which is common with Panpit) in accompaniment with their Panhypopituitarism, the spectrum of suitable career opportunities would not be as broad as they could not join the US military or air force, for example. Otherwise, I believe the doors are open to less impacted Panhypopituitarism patients. I, personally, would avoid strenuous and tasking jobs, though, as they may make the common symptoms of fatigue/adrenal fatigue, and chronic pain worse, but to each their own. Panhypopituitarism patients also have to be careful with illness, though as it can be quite dangerous and, in my experience, colds and other sicknesses can last for months with this disease, hindering your ability to work.