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How is Stiff Person Syndrome diagnosed?

See how Stiff Person Syndrome is diagnosed. Which specialists are essential to meet, what tests are needed and other useful information for the diagnosis of Stiff Person Syndrome

Stiff Person Syndrome diagnosis
6 answers
EMG studies.
Symptoms.
GAD levels.

Posted Feb 28, 2017 by Loretta 1000
A blood test for antibodies to GAD, an EMG, which should be done by someone looking for SPS. A lumber Puncture to rule out other conditions. The patient should be under the care of a neurologist.
A useful port of call is to join a support group as most are able to answer questions posed, and give caring support.

Posted Mar 1, 2017 by Liz 1000
It takes on average 7 years, many specialists and misdiagnosis' stop get a diagnosis.
It is usually diagnosed by a neurologist.
My experience, I was referred to a neurologist by an orthopedic surgeon after years of being treated for muscle stiffness and rigidity. She was able to diagnose me based on a neurological exam, the way I walked and my posture. She prescribed me with a very low dose of Valium while she ordered blood tests, specifically an anti-gad 65 blood test and a paraneoplastic and ANA panel. When the tests came back she scheduled an eeg. She ran tests to rule out other diseases before finally diagnosing me with Stiff Person Syndrome.

Posted Mar 2, 2017 by Michelle 1500
In the United States there is a test, the Gad65 test which is a blood test. If you are symptomatic and have an elevated gad65, that is the disagosis. However a gad65 can also be positive if the patient has diabetes so the levels would need to be looked at, however SPS and diabetes coincide more often than not. Patients don't always test positive and are diagnosed based on their symptoms. Spasms, weakness, falls and many more.

Posted Mar 4, 2017 by Jasmine Nardone-Franco 1430
History of autoimmune disease such as type 1 diabetes or as in my case hashimoto's thyroiditis. I was misdiagnosed with atypical Parkinsonism, multiple system atrophy and even psychogenic etiology by a Mayo neurologist in Florida. Vanderbilt finally diagnosed me EMG testing showing continuous motor unit activity in my abdominal and paraspinal muscles as well as testing for GAD 65 antibody which was high. Clinical presentation was classical, but too few physicians have experience with SPS or take the time to actually do a proper physical exam and ask pertinent questions.

Posted Dec 24, 2021 by Pathdoc 2500
Translated from spanish Improve translation
If you have not never seen it is difficult to diagnose. The average is of 13 years of evolution. A patient with spasms, rigidity, and falls to be frequent, that are triggered with emotions, it is immediately diagnosed with a neurosis or personality disorder. There are two fundamental tests: EMG and anticuercos antiGad. In some cases the levels are normal. In the same way there are that ask for antibodies antifisisinas. If you are positive these last, it would be a process s.

Posted Sep 18, 2017 by Fernando Vela Vallejo 3250

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