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What are the latest advances in Acute Respiratory Distress Syndrome?
Here you can see the latest advances and discoveries made regarding Acute Respiratory Distress Syndrome.
Use of ECMO
Posted May 22, 2017 by Karin 2002
Acute respiratory distress syndrome was first described in 1967 by Ashbaugh et al.[10][41] Initially there was no clearly established definition, which resulted in controversy regarding the incidence and death of ARDS.
In 1988, an expanded definition was proposed, which quantified physiologic respiratory impairment.
1994 American-European Consensus Conference on ARDS[edit]
In 1994, a new definition was recommended by the American-European Consensus Conference Committee [3][10] which recognized the variability in severity of pulmonary injury.[42]
The definition required the following criteria be met:
acute onset, persistent dyspnea
bilateral infiltrates on chest radiograph consistent with pulmonary edema
hypoxemia, defined as PaO
2:FiO
2 < 200 mmHg (26.7 kPa)
absence of left atrial (LA) hypertension
pulmonary artery wedge pressure < 18 mmHg (obtained by pulmonary artery catheterization)
if no measured LA pressure available, there must be no other clinical evidence to suggest elevated left heart pressure.
If PaO
2:FiO
2 < 300 mmHg (40 kPa), then the definitions recommended a classification as "acute lung injury" (ALI). Note that according to these criteria, arterial blood gas analysis and chest X-ray were required for formal diagnosis. Limitations of these definitions include lack of precise definition of acuity, nonspecific imaging criteria, lack of precise definition of hypoxemia with regards to PEEP (affects arterial oxygen partial pressure), arbitrary PaO
2 thresholds without systematic data.[4
In 1988, an expanded definition was proposed, which quantified physiologic respiratory impairment.
1994 American-European Consensus Conference on ARDS[edit]
In 1994, a new definition was recommended by the American-European Consensus Conference Committee [3][10] which recognized the variability in severity of pulmonary injury.[42]
The definition required the following criteria be met:
acute onset, persistent dyspnea
bilateral infiltrates on chest radiograph consistent with pulmonary edema
hypoxemia, defined as PaO
2:FiO
2 < 200 mmHg (26.7 kPa)
absence of left atrial (LA) hypertension
pulmonary artery wedge pressure < 18 mmHg (obtained by pulmonary artery catheterization)
if no measured LA pressure available, there must be no other clinical evidence to suggest elevated left heart pressure.
If PaO
2:FiO
2 < 300 mmHg (40 kPa), then the definitions recommended a classification as "acute lung injury" (ALI). Note that according to these criteria, arterial blood gas analysis and chest X-ray were required for formal diagnosis. Limitations of these definitions include lack of precise definition of acuity, nonspecific imaging criteria, lack of precise definition of hypoxemia with regards to PEEP (affects arterial oxygen partial pressure), arbitrary PaO
2 thresholds without systematic data.[4
Posted Jun 7, 2017 by Lyda 2442
Unfortunately there have not been a lot of advancement due to the number of cases per year. This is sad snd disappointing considering the long term affects this causes in most patients
Posted Dec 17, 2020 by tbrannock 2500
