Yes, Addison's Disease is often genetic. I went to the Mayo Clinic, and they did a genetic test. My Endocrinologist reported to me that I have genetic Addison's Disease. The doctor stated that the gene for Addison's is related to the genes for Celiac Disease. My mother had Celiac Disease and died with every symptom listed for Addison's Disease.
See the following research on Addison's and Celiac:
"In conclusion, of the previously reported autoimmune endocrinopathies, Addison's disease has the strongest association with coeliac disease. This is likely to be related to their similar genetic backgrounds, although a cause‐and‐effect relationship between gluten exposure and autoimmunity has been raised. We recommend that coeliac serology be incorporated into the routine screen for autoimmune conditions in patients with autoimmune Addison's disease.
Address correspondence to Professor F. Shanahan, Professor of Medicine/Consultant Gastroenterologist, Department of Medicine, Cork University Hospital, Cork, Ireland. e‐mail:
[email protected]" (https://academic.oup.com/qjmed/article/95/2/79/1528619?login=false)