My daughter has first manifestation when she was 7 years old, 3 months after that she had pneumonia, today she has some crisis but in the first years she suffered enough , in 2012 she used interferon and this medicine was perfect for her, she used 2 years and she had no crisis for 4 years, but this year the crisis began, and she will start with interefon again. She has mouth ulcers and vaginal sores, but she had stomach's cancer.