Generally, CH is a lifelong problem. Potential outcomes include the following:
Recurrent attacks
Prolonged remissions
Possibility of transformation of an episodic cluster to a chronic cluster and vice versa
About 80% of patients with episodic CH maintain the episodic form of the disorder. In 4-13%, episodic CH eventually transforms into chronic CH. Intermediate (mixed) forms may also develop. Prolonged, spontaneous remissions occur in as many as 12% of patients, particularly in those with episodic CH. Chronic CH is more relentless and may persist in this form in as many as 55% of cases. Less frequently, chronic CH may remit into an episodic form