I get extremely uncomfortable, itchy, and swell up when I go out in the winter with CU but it doesn't stop me. I have had it for years so I am just used to it now, it doesn't get in the way of my life, besides losing an ROTC scholarship when I was first diagnosed because I could not pass the medical waiver :/ I still go skiing, sledding, and running in the winter, just for shorter periods of time with breaks to warm myself up. If you put effort into moving on, I have found it becomes a small annoyance- from a big picture perspective. The most frustrating part is explaining to people why you don't want to go out into the cold "I am allergic to the cold" is usually responded to with "hahaha yeah, me too!".