It is diagnosed by its characteristics and symptoms, i.e., lesions, drainage, and fatigue. There is no blood test to determine HS within the body. However, caution when visiting a doctor. Many doctors do not know what HS is, nor do they recognize it. Many patients have been misdiagnosed with STDs or herpes. Dermatologists usually know more about HS than doctors. When you make an appointment, inquire about the derm's or doctor's knowledge of HS before seeing her/him.