I am an MZ carrier of Alpha1 Antitripsyn Deficiency with mild copd and also have narcolepsy. I try my best to live a life free from meds but understand that is not always fully possible. My father died from lung disease due to Alpha1 around age 60 after 12 years with a lung transplant! My younger brother has MS, and my family is the absolute royalty of all things auto immune. Thanks, genes!