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What is Pemphigus

Pemphigus description. Find out what Pemphigus is and know more about it.

What is Pemphigus

Pemphigus is a rare autoimmune disorder that affects the skin and mucous membranes. It is characterized by the formation of painful blisters and erosions on the skin and inside the mouth, nose, throat, and genitals. These blisters occur due to the immune system mistakenly attacking healthy cells in the skin and mucous membranes.



Pemphigus can be classified into several types, including pemphigus vulgaris and pemphigus foliaceus. Pemphigus vulgaris is the most common and severe form, affecting both the skin and mucous membranes. Pemphigus foliaceus primarily affects the skin and is usually less severe.



The exact cause of pemphigus is unknown, but it is believed to involve a combination of genetic and environmental factors. The condition can be triggered or exacerbated by certain medications, infections, or exposure to ultraviolet light.



Diagnosis of pemphigus involves a thorough physical examination, biopsy of the affected skin or mucous membrane, and various laboratory tests. Treatment typically involves the use of immunosuppressive medications to control the immune response and reduce blister formation. Additionally, proper wound care and pain management are essential.



Living with pemphigus can be challenging, as it can significantly impact a person's quality of life. It is important for individuals with pemphigus to work closely with healthcare professionals to manage their condition and seek support from patient advocacy groups.


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What is Pemphigus

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World map of Pemphigus

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Stories of Pemphigus

PEMPHIGUS STORIES
Pemphigus stories
In April, 2012 I saw my dentist about a sore which didn't heal and was given antibiotics. When these made no difference, I went back to the dentist. She seemed unsure what to do and I pushed for an investigation, saying "Are you sure it's not cancer?...
Pemphigus stories
Diagonsed with Lupus originally, but the medicines were not working.  After 4 skin biopsies, PE was confirmed.  I've been through Imuran, CellCept, Plaquenil, Dapsone, and Plaquenil/Dapsone combined.  Have been on steriods since confirmation.  St...
Pemphigus stories
I was diagnosed with Bullous Pemphigoid in 2008. Now in remission after treatment for 2 years at OHSU with Prednisone, Tetracycine and Cellcept.
Pemphigus stories
Not unlike other patients, I fist had what I thought was an insect bite.  Then it grew and grew on upper back till I was covered in 3" blisters. Went to Bevelry Hills dermatologist. Misdiagnosed for 4 months.  Blood tests said PV; biopsy said negat...
Pemphigus stories
I was diagnosed with the disease in 2012, by a eye doctor in Greenville SC. He referred me too Emory University Hospital in Atlanta Georgia, my doctors are Dr Feldman (Derm) and Dr Dholakia (Optomoligist), I have had seven treatments of Rituxamab ove...

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