Pemphigus is a rare autoimmune disorder that affects the skin and mucous membranes. It is characterized by the formation of painful blisters and erosions on the skin and inside the mouth, nose, throat, and genitals. These blisters occur due to the immune system mistakenly attacking healthy cells in the skin and mucous membranes.
Pemphigus can be classified into several types, including pemphigus vulgaris and pemphigus foliaceus. Pemphigus vulgaris is the most common and severe form, affecting both the skin and mucous membranes. Pemphigus foliaceus primarily affects the skin and is usually less severe.
The exact cause of pemphigus is unknown, but it is believed to involve a combination of genetic and environmental factors. The condition can be triggered or exacerbated by certain medications, infections, or exposure to ultraviolet light.
Diagnosis of pemphigus involves a thorough physical examination, biopsy of the affected skin or mucous membrane, and various laboratory tests. Treatment typically involves the use of immunosuppressive medications to control the immune response and reduce blister formation. Additionally, proper wound care and pain management are essential.
Living with pemphigus can be challenging, as it can significantly impact a person's quality of life. It is important for individuals with pemphigus to work closely with healthcare professionals to manage their condition and seek support from patient advocacy groups.