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What are the latest advances in Premenstrual Dysphoric Disorder?

Here you can see the latest advances and discoveries made regarding Premenstrual Dysphoric Disorder.

Latest progress of Premenstrual Dysphoric Disorder
4 answers
Treatment consists of taking contraceptive pills for hormones balance and antidepressants for the most difficult days.
Latest treatments include mindfulness meditation to control the cortisol levels in the body.

Posted Jul 24, 2017 by Limerencia 2070
There are lots of apps to use to help track your symptoms, and you can do online CBT courses to help manage your symptoms

Posted Sep 10, 2017 by son678 2000
Medication may be used for people with severe and debilitating symptoms. Selective serotonin reuptake inhibitors (SSRIs) are the first-line medication.[4] The U.S. Food and Drug Administration (FDA) has approved four SSRIs for the treatment of PMDD: Fluoxetine (available as generic or as Prozac or Sarafem), sertraline (Zoloft), paroxetine (Paxil), and escitalopram oxalate (Lexapro).[18] Unlike treatments for depressive disorders, SSRIs do not need to be taken daily but instead can be taken only in the luteal phase or during PMDD symptoms.[3] This is because those who respond to SSRIs usually experience symptoms relief within 1–2 days.[19] Studies in rats suggest this rapid response to SSRIs is due to the elevation of the neuroactive progesterone metabolite allopregnanolone in the brain, rather than serotonin.[20][21] Luteal phase dosing can be started 14 days before menses and subsequently discontinued after start of menstrual flow.[18] People taking SSRIs to ease PMDD generally report >50% alleviation in symptoms, which was significant improvement compared to placebo.[19]

Although less studied, SNRIs have also shown benefit in PMDD. In a randomized, controlled clinical trial of people with PMDD, 60% of the people taking venlafaxine improved versus 35% on placebo. Improvement was noticed during the first treatment cycle with 80% symptom reduction.[22]

Another FDA approved treatment for PMDD is the oral contraceptive with ethinylestradiol and drospirenone, a novel progestin.[18] It has been shown that hormonal birth control containing drospirenone and low levels of estrogen helps relieve severe PMDD symptoms, for at least the first three months it is used.[23] The idea behind using oral contraceptives is to suppress ovulation by controlling sex hormone fluctuations during the luteal phase.

Psychotherapy Edit
Cognitive behavioral therapy (CBT) has been shown to be effective in PMS and is suggested as a successful adjunct to SSRI treatment. CBT is an evidence-based treatment approach for treating depression and focuses on the link between mood, thoughts, and actions to help patients address current issues and symptoms. When CBT was compared to SSRI alone or in combination with SSRI, groups receiving CBT had significant improvement of PMS symptoms. Through the practice of CBT, patients are better able to recognize and modify recurrent issues as well as thought and behavior patterns that interfere with functioning well or that make depressive symptoms worse.[24]

Alternative medicine Edit
There have been some nutritional supplements that have been shown to help alleviate the symptoms of PMDD. In 1998, a placebo-controlled, randomized trial of 720 people with PMDD found that calcium carbonate demonstrated up to a 50% reduction in symptoms, compared with a 30% reduction in the control group.[25][26][27] Herbal treatments that have shown promise in PMDD include chasteberry (Vitex agnus castus), St. John's wort (Hypericum perforatum), and ginkgo (Ginkgo biloba). Studies have been conducted on the efficacy of chasteberry and gingko, but as of this writing, no randomized controlled trial has been conducted on the efficacy of St. John's wort in alleviating PMDD symptoms

Posted Oct 22, 2017 by Deanna 2550
Premenstrual syndrome (PMS) is characterized by the occurrence of a constellation of symptoms temporally associated with the menstrual cycle. Symptoms of PMS include physical and mood changes that peak premenstrually and resolve shortly following the onset of menstrual bleeding. Historical descriptions of PMS are shrouded in mythology, and, previously, the scientific understanding of PMS was limited. The term premenstrual syndrome was used in 1931 by Greene and Dalton to describe a constellation of physical and emotional symptoms.15 The abbreviation “PMS” subsequently became a term widely recognized by the public and used by health care providers. The evaluation of PMS was hampered by the lack of agreed upon definitions or diagnostic criteria, and treatment protocols were often based on poorly designed studies. Advances in the understanding of PMS have accelerated in the past decade owing to increased attention placed on the definition and diagnostic criteria, the development of validated PMS calendars, inroads into the understanding of the underlying pathophysiology, and significant breakthroughs in therapy. The most recent scientific investigations have focused on patients with premenstrual dysphoric disorder (PMDD), a severe form of PMS with strict diagnostic criteria. To this day, the precise pathophysiology of PMS has not yet been elucidated; however, significant strides have been made in the diagnosis, treatment, and understanding of PMS.
https://www.sciencedirect.com/science/article/pii/S0889854505701601

Posted Aug 9, 2018 by April 3000

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Stories of Premenstrual Dysphoric Disorder

PREMENSTRUAL DYSPHORIC DISORDER STORIES
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My life has been torn apart from PMDD. I have recently come out of homelessness from it and trying to get back on my feet so I can take care of my 7 year old on my own. I can barely function and I am running out of options. I’ve tried every single...
Premenstrual Dysphoric Disorder stories
I was late teens, early twenties when my obgyn suggested I suffered from pmdd. I saw my family doctor who didn't know much of this and said if so we can treat the symptoms. I've tried many methods for relief. I have cycles that are worse than others ...
Premenstrual Dysphoric Disorder stories
8 years of hell and going. I have tried it all. Looking for new ideas! HELP
Premenstrual Dysphoric Disorder stories
Well, I was lucky to be diagnosed right away by my primary care in 2004. What wasn't so lucky is that the only option she gave me at the time was antidepressants. Having a family history of depression amongst other things and seeing that it was not h...
Premenstrual Dysphoric Disorder stories
I have been saying to health professionals for years my depression and anxiety is at its worst the week or so before my period. I tell people I suffer severe pms and I only recently heard of PMDD. After reading all the changes that occurred I realise...

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