What is the prevalence of HFE hereditary haemochromatosis?
How many people does HFE hereditary haemochromatosis affect? Does it have the same prevalence in men and women? And in the different countries?
The prevalence of HFE hereditary haemochromatosis varies among different populations. In individuals of Northern European descent, it is estimated to affect approximately 1 in 200 individuals, making it one of the most common genetic disorders. However, the prevalence may be lower in other ethnic groups. This condition is characterized by excessive iron absorption, leading to iron overload in various organs. Early detection and management are crucial to prevent complications such as liver disease, diabetes, and heart problems.
HFE hereditary haemochromatosis is a genetic disorder characterized by excessive absorption of dietary iron, leading to iron overload in various organs. It is considered one of the most common genetic disorders in people of European descent. The prevalence of HFE hereditary haemochromatosis varies among different populations.
In Caucasians of Northern European descent, the prevalence is estimated to be around 1 in 200 individuals. However, it is important to note that not all individuals with the HFE gene mutation will develop symptoms or complications associated with iron overload.
Although less common, HFE hereditary haemochromatosis can also occur in individuals of other ethnic backgrounds, including African, Asian, and Hispanic populations. The prevalence in these populations is generally lower compared to Caucasians.
Early diagnosis and treatment are crucial in managing HFE hereditary haemochromatosis. Genetic testing and regular monitoring of iron levels can help identify individuals at risk and prevent complications associated with iron overload.
In Ireland, the genetic risk is about 1 in 80.
In other northern European countries and countries with high levels of European migration like Australia, Canada, USA, New Zealand, South Africa and Brazil the prevalence is quite high.
In Australia for instance, the risk is about 1 in 200.
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